What if the parts of our lives we've accepted as normal were totally different? What if dogs had never been domesticated? Or humans had no sense of flavor...what would've happened to the spice trade? And how would that have shaped the future of the world? Join CNN's Chris Cillizza as he speaks with journalists, experts and forward-thinking futurists to help us envision what might have been — and how even a small shift in the status quo could change our world completely.

New episodes start Monday October 3, 2022.

Plastics are everywhere. They’re in our shoes and clothes. They’re in our cars, our airplanes and our cellphones. They’re in our hospitals and schools. They’re also in our bodies and in our oceans. The invention of this versatile material radically changed our world. But what if plastic didn’t exist? What would our world look like today? This week on Downside Up, Chris Cillizza is joined by Allison Cobb, author “Plastic: An Autobiograpy,” Erica Cirino, author of  “Thicker Than Water: The Quest for Solutions to the Plastic Crisis,” and Winnie Lau who studies plastics with the Pew Charitable Trusts, to reimagine the world without plastics.

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